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Roland B Walter Selected Research

Gemtuzumab (Mylotarg)

6/2022Phase 1/2 Trial of CLAG-M with Dose-Escalated Mitoxantrone in Combination with Fractionated-Dose Gemtuzumab Ozogamicin for Newly Diagnosed Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms.
3/2021The evolving use of gemtuzumab ozogamicin in acute myeloid leukemia.
1/2021Budget Impact Analysis of Gemtuzumab Ozogamicin for the Treatment of CD33-Positive Acute Myeloid Leukemia.
1/2021Targeting the membrane-proximal C2-set domain of CD33 for improved CD33-directed immunotherapy.
8/2017CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531.
12/2016Characterization of CD33/CD3 Tetravalent Bispecific Tandem Diabodies (TandAbs) for the Treatment of Acute Myeloid Leukemia.
7/2016Expression and functional characterization of CD33 transcript variants in human acute myeloid leukemia.
6/2015Update on antigen-specific immunotherapy of acute myeloid leukemia.
6/2014Biting back: BiTE antibodies as a promising therapy for acute myeloid leukemia.
5/2014Mcl-1 dependence predicts response to vorinostat and gemtuzumab ozogamicin in acute myeloid leukemia.
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Roland B Walter Research Topics

Disease

117Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2022 - 05/2003
33Neoplasms (Cancer)
06/2022 - 11/2005
18Leukemia
01/2022 - 09/2003
13Residual Neoplasm
01/2018 - 06/2010
11Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2022 - 06/2011
7Hematologic Neoplasms (Hematological Malignancy)
01/2021 - 04/2010
5Cytopenia
01/2019 - 07/2014
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2020 - 08/2013
4Bites and Stings (Sting)
01/2018 - 01/2014
3Infections
01/2022 - 04/2014
3Graft vs Host Disease (Graft-Versus-Host Disease)
01/2020 - 01/2008
3Neutropenia
01/2020 - 08/2013
2Lymphoma (Lymphomas)
01/2019 - 08/2013
2Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive)
01/2017 - 03/2003
2Exanthema (Rash)
01/2016 - 04/2014
2Acute Promyelocytic Leukemia
01/2016 - 06/2012
2Ovarian Neoplasms (Ovarian Cancer)
10/2014 - 10/2002
2Breast Neoplasms (Breast Cancer)
01/2014 - 11/2005
2Atherosclerosis
01/2008 - 10/2003
1Bacteremia
01/2022
1Mycoses (Diseases, Fungus)
01/2022
1Cytokine Release Syndrome
11/2021
1Invasive Fungal Infections
01/2021
1Bone Marrow Failure Disorders
01/2021
1Multiple Myeloma
11/2020
1Non-Hodgkin Lymphoma (Lymphosarcoma)
11/2020
1Mucositis
01/2020
1Fatigue
01/2020
1Fever (Fevers)
01/2020
1Lymphopenia (Lymphocytopenia)
01/2020
1Febrile Neutropenia
01/2020
1Pneumonia (Pneumonitis)
01/2020
1Hypophosphatemia
01/2020
1Interstitial Lung Diseases (Interstitial Lung Disease)
01/2020
1Thrombocytopenia (Thrombopenia)
01/2020
1B-Cell Leukemia (Leukemia, B Cell)
01/2019

Drug/Important Bio-Agent (IBA)

24Gemtuzumab (Mylotarg)FDA Link
06/2022 - 08/2003
17Immunoconjugates (Immunoconjugate)IBA
01/2021 - 08/2003
9AntigensIBA
01/2022 - 01/2015
8Cytarabine (Cytosar-U)FDA LinkGeneric
06/2022 - 04/2015
6Granulocyte Colony-Stimulating Factor (G-CSF)IBA
06/2022 - 04/2014
6Mitoxantrone (Novantrone)FDA LinkGeneric
06/2022 - 11/2013
5Proteins (Proteins, Gene)FDA Link
12/2020 - 08/2003
5Pharmaceutical PreparationsIBA
07/2014 - 10/2002
4CladribineFDA LinkGeneric
06/2022 - 11/2018
4AntibodiesIBA
01/2022 - 01/2013
4Biomarkers (Surrogate Marker)IBA
12/2021 - 08/2013
4Bispecific AntibodiesIBA
01/2019 - 07/2014
4VitaminsIBA
12/2013 - 06/2011
3Chimeric Antigen ReceptorsIBA
12/2020 - 07/2014
3Monoclonal AntibodiesIBA
01/2019 - 01/2011
3VorinostatFDA Link
05/2014 - 05/2012
3Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2014 - 11/2005
2Complement System Proteins (Complement)IBA
01/2022 - 11/2020
2Indicators and Reagents (Reagents)IBA
01/2022 - 01/2018
2venetoclaxIBA
11/2020 - 01/2019
2Biological ProductsIBA
01/2020 - 03/2013
2Differentiation AntigensIBA
01/2018 - 07/2014
2MEF2 Transcription FactorsIBA
11/2016 - 10/2015
2Clofarabine (Clolar)FDA Link
08/2015 - 04/2015
2AMG 330IBA
01/2015 - 01/2014
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
10/2014 - 06/2011
2ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2014 - 11/2005
2Adenosine Triphosphate (ATP)IBA
01/2014 - 11/2005
2Cyclosporine (Ciclosporin)FDA LinkGeneric
11/2013 - 11/2005
2Acetaminophen (Paracetamol)FDA LinkGeneric
12/2011 - 06/2011
2NeopterinIBA
01/2008 - 10/2003
2Scavenger Receptors (Scavenger Receptor)IBA
02/2006 - 05/2003
1posaconazoleFDA Link
01/2022
1Surface Antigens (Surface Antigen)IBA
01/2022
1AstatineIBA
01/2022
1Fluconazole (Zonal)FDA LinkGeneric
01/2022
1insulin receptor-related receptor (IRR)IBA
11/2021
1tocilizumab (atlizumab)FDA Link
11/2021
1Dexamethasone (Maxidex)FDA LinkGeneric
11/2021
1CalicheamicinsIBA
12/2020
1Myeloid Cell Leukemia Sequence 1 ProteinIBA
11/2020
1Protein Isoforms (Isoforms)IBA
01/2020
1gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
01/2020
1DecitabineFDA Link
01/2020
1BilirubinIBA
12/2019
1Immunoglobulin G (IgG)IBA
01/2019
1AnthracyclinesIBA
11/2018
1vadastuximab talirineIBA
01/2018
1CPX-351IBA
01/2018
1pyrrolo(2,1-c)(1,4)benzodiazepineIBA
01/2018

Therapy/Procedure

46Therapeutics
01/2022 - 08/2003
24Drug Therapy (Chemotherapy)
12/2022 - 11/2005
18Cell Transplantation
01/2022 - 03/2011
11Induction Chemotherapy
01/2022 - 06/2011
11Immunotherapy
11/2021 - 05/2008
3Radioimmunotherapy
01/2022 - 04/2010
3Ambulatory Care (Outpatient Care)
01/2021 - 01/2016
2Hematopoietic Stem Cell Transplantation
12/2020 - 05/2014
2Investigational Therapies (Experimental Therapy)
03/2016 - 05/2014
2Transplantation
02/2016 - 08/2015
1Catheters
01/2022
1Drug Tapering
11/2021
1Cell- and Tissue-Based Therapy (Cell Therapy)
12/2020
1Salvage Therapy
05/2016